GutOpinion

Red cells, red flags: are we harming stable patients with outdated transfusion thresholds?

The 2022 UK-wide acute upper gastrointestinal bleeding (AUGIB) audit by Nigam and colleagues is a landmark. With ...
Gut

Response to ‘Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data’

We read with great interest the study by Van der Voort et al ,1 which compared rectal versus colonic submucosal cancer rates ...
Gut

Potential of GDF15 goes beyond its role as a non-invasive biomarker for MASLD

We read with great interest the article of Ratziu and colleagues, who evaluated the potential of thrombospondin-2 (TSP2), insulin-like growth factor binding protein 7, CD163 and growth differentiation ...
Gut

Intraperitoneal translocation of gut microbiota induces NETosis and promotes endometriosis

Background Endometriosis is a debilitating gynaecological disorder with an elusive pathogenesis. While gut microbiota dysbiosis has been implicated, the causal role of gut-peritoneum microbial ...
Gut

Gut microbe alleviates stress-related cancer metastasis by oleic acid degradation

Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...
Gut

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection

Background Chronic hepatitis B virus (HBV) infection disproportionately affects people living with HIV, who are often excluded from functional cure studies. Objective This study investigates CD8+ T ...
gut.bmj

Alterations of gut microbiome in autoimmune hepatitis

Objective The significance of the liver-microbiome axis has been increasingly recognised as a major modulator of autoimmunity. The aim of this study was to take advantage of a large well-defined ...
gut.bmj

Apoptosis: a mechanism of acute and chronic liver injury

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...
gut.bmj

The Vienna classification of gastrointestinal epithelial neoplasia

BACKGROUND Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of oesophageal, ...
gut.bmj

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial

Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS ...
gut.bmj

Single-biopsy epigenetic profiling reveals persistent DNA methylation and gastric cancer risk after Helicobacter pylori eradication

Gastric cancer is a major global health concern, with ongoing efforts focused on screening and eradicating Helicobacter pylori infection.1 However, H. pylori infection is typically acquired during ...
gut.bmj

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model

Correspondence to Professor Jin-Woo Bae, Department of Life and Nanopharmaceutical Sciences and Department of Biology, Kyung Hee University, Seoul 02447, Republic of Korea; baejw{at}khu.ac.kr; ...