The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

By setting up both reactions side by side in a test tube, the team revealed a literal tug-of-war between two DNA-repair pathways acting on the same HTT repeat. Which side wins likely determines ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...

The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism ...

Two studies provide a radically new picture of how bacterial cells continually repair damaged sections (lesions) in their DNA. Two studies provide a radically new picture of how bacterial cells ...

A Florida State University College of Medicine researcher has made a discovery that alters our understanding of how the body’s DNA repair process works and may lead to new chemotherapy treatments for ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

Faulty DNA damage repair can lead to many types of cancer, neurodegenerative diseases, and other serious disorders. Investigators have developed high-throughput microscopy and machine learning systems ...