Oocyte in vitro maturation is a technique in assisted reproductive technology. Thousands of genes show abnormally high expression in in vitro maturated metaphase II (MII) oocytes compared to those ...

Age-related deterioration of oocyte quality is a major cause of female infertility. Aged oocytes exhibit meiotic abnormalities and aneuploidy, yet the molecular mechanisms underlying these defects ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

A lineage-tracing study in mice shows that oocytes activated early in life can persist for nearly the entire reproductive ...

Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

Researchers from Japan and France have successfully reconstituted the development of mouse egg cells, known as oocytes, from embryonic stem cells entirely in vitro, without the need for ovarian ...

When the female germline develops, oocyte growth is accompanied by many changes in gene expression, however, the regulatory networks that control this process have not been determined. Now, a group of ...

The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers ...

(a) Fluorescence images showing the chromatin in FGO stained with DAPI. Scale bar, 20 μm. Yellow triangles indicate DAPI-dense heterochromatin foci and the red triangles denote the nucleoli or NLBs.

Title] Male obesity is associated with delayed embryonic development and increased miscarriage risk even in oocyte donation ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

A seven-day course of the mitochondria-targeting peptide elamipretide restored oocyte quality, embryo development and ...