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Predictions, picks and odds for NFL Week 15 game

NFL Week 15 picks: Upset and score predictions, matchup breakdowns for every game

NFL.com editors Ali Bhanpuri, Tom Blair, Brooke Cersosimo, Gennaro Filice and Dan Parr will predict the winner of every game in the 2025 NFL season, using the unbeatable combo of football analysis and...

· 16h · on MSN

Week 15 NFL odds, lines, best bets, predictions: Computer model backing Giants and Saints

SportsLine · 18h

NFL odds, lines, spreads: 2025 Week 15 picks, predictions from proven model

· 11h

NFL 2025 Week 15 odds: Chiefs vs. Chargers spread, line, over/under

AFC West opponents square off when the Kansas City Chiefs (6-7) host the Los Angeles Chargers (9-4) on Sunday, December 14, 2025 at GEHA Field at Arrowhead Stadium.

· 1d

Tom Brady's NFL Power Rankings: Packers Rise After Bears Win, But Are They NFC's Best?

· 5h

Chargers vs. Chiefs: Thursday injury report

· 6h

Chargers face reeling Chiefs taking nothing for granted

They are still playing at a high level offensively despite a 6-7 record that would indicate otherwise.

· 1d

AP Mailbag: Chiefs’ rookie Esa Pole had a good game against the Texans

· 1d

Chargers vs. Chiefs: 5 key things to know about LA's Week 15 opponent

20hon MSN

NFL Week 15 picks: Rams prevail over Lions; Broncos defeat Packers

Sam Farmer makes his picks and predictions for Week 15 of the NFL season, with the Rams defeating the Detroit Lions and the Broncos winning their 11th straight game.

1don MSN

NFL Week 15 picks and predictions, straight-up and ATS: Bills-Patriots, Packers-Broncos lead huge slate

Games are always going to have big stakes when you get to something like Week 15, be those for the NFL Playoffs or looking further ahead to the NFL Draft. But t